2. Signaling Pathways
  3. GPCR/G Protein
  4. Bombesin Receptor
  5. Bombesin Receptor Chemical

Bombesin Receptor Chemical

Bombesin Receptor Chemical (1):

Cat. No. Product Name Effect Purity
  • HY-P5520
    GB-6
    		Chemical
    GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects.